What is Celebrex?
Celebrex has the generic name of celecoxib, and is marketed by Pfizer. It is a member of the class of drugs known as non-steroidal anti-inflammatory drugs, also known as NSAIDs. It and other NSAIDs are used in the treatment of pain and inflammation. Celebrex is an extremely popular drug that has been widely prescribed to over 29 million people since the FDA approved it in 1998. Sales of Celebrex have resulted in huge profits for Pfizer. Celebrex is specifically prescribed for the treatment of acute pain, symptoms of various types of arthritis including osteoarthritis, ankylosing spondylitis, and rheumatoid arthritis, in addition to severe menstrual pain and discomfort. It has also been prescribed to decrease the growth of colon polyps in those people who suffer from Familial Adenomatous Polyposis.
Celebrex is what is known as a Cox-2 inhibitor. Other Cox-2 inhibitors include the prescription drugs Vioxx and Bextra, both of which were removed from the market after links to cardiovascular disease were discovered. Celebrex is designed to assist in pain and inflammation relief by blocking the Cox-2 enzyme that creates prostaglandins in the body. Decreasing these prostaglandins helps the body by reducing pain and inflammation.
Celebrex Side Effects
Some of the common side effects of Celebrex may include headache, diarrhea, stomach pain, nausea, sinus inflammation and upper respiratory tract infection. Similarly to other NSAIDs, there may be a risk of more serious side effects such as liver damage, stomach ulcers, kidney damage, and fluid retention. People with pre-existing kidney and liver ailments may be at an increased risk of additional problems. Celebrex is also linked to the possible side effect of potentially fatal stomach or intestinal bleeding.
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Celebrex Black Box Warning
Recently, Celebrex has been recommended by the FDA to receive a "black box warning." The black box warning is the most serious warning that the FDA can provide, short of having the drug recalled from the market. The new warning for Celebrex concerns the possible link between the drug and serious cardiovascular problems including heart attack and stroke. The possible link between Celebrex and heart problems has been a frequent topic in the media, as the drug Vioxx was pulled from the market after it was linked to cardiovascular problems. Vioxx is also a Cox-2 inhibitor, similar to Celebrex. In a National Cancer Institute Study with approximately 3,600 people taking part, patients taking 400 milligrams of Celebrex daily were 2.5 times more likely to suffer from heart problems than those patients taking a placebo. Patients taking 800 milligrams of Celebrex per day were as much as 3.4 times more likely to suffer heart problems than the placebo group.
Questions and Consultations
If you or a family member has used the prescription drug Celebrex and noticed adverse side effects, such as stroke or heart attack, you should contact a physician immediately. If you would like to discuss your rights, are interested in more information on Celebrex litigation, or if you have information about the cases that you would like to share with us, please fill out the short evaluation form below and a member of Seeger Weiss LLP?s experienced staff will call you to discuss your potential rights concerning Celebrex. Attorney consultations incur no obligation on your part and all initial consultations are free of charge and do not create an attorney-client relationship. Seeger Weiss LLP has office locations in both New York and New Jersey and its attorneys practice in courts throughout the country.
Further Reading:
http://www.fda.gov/cder/drug/infopage/celebrex/celebrex-ptsk.htm
http://www.fda.gov/cder/drug/infopage/COX2/default.htm
Link To Lawyer Seek's Celebrex Content:
<a href='http://www.lawyerseek.com/Practice/Pharmaceutical-Injury-C1/Celebrex-P27/'>Celebrex: Lawyer Seek</a> |
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